Article
Bi-directional two-sample Mendelian randomization identifies causal association of depression with temporomandibular disorders.
Journal of oral rehabilitation - 1 Sept 2024
Que Hanxin, Zhang Qinglian, Xu Shengming, Chu Tengda, Xu Leyan, Wang Yi
Abstract excerpt
BACKGROUND: Depression and anxiety have been suggested to be associated with temporomandibular disorders (TMD) in observational studies. However, the causal association and the direction in the relationship between depression/anxiety and TMD remain unknown. OBJECTIVES: This study investigated the potential causal relationship between depression/anxiety and TMD with two-sample bi-directional Mendelian...
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