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Dynamic analysis of predictive biomarkers for radiation therapy efficacy in non-small cell lung cancer patients by next-generation sequencing based on blood specimens.

Pathology, research and practice - 1 Jan 2024

Zhang Xuemei, Huang Xu, Cao Yang, Mao Yuxin, Zhu Yingying, Zhang Qian, Zhang Tao, Chang Lele, Wang Chunbo

Abstract excerpt

PURPOSE: Radiotherapy plays an important role in the treatment of non-small cell lung cancer, and the aim of this study was to explore the potential association of single gene mutation or pathway mutations with radiotherapy response using targeted next-generation sequencing (NGS) testing of peripheral blood specimens. MATERIAL AND METHODS: We performed NGS containing 425 genes on peripheral blood specimens from...

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Identifiers

PMID: 38064866
DOI: 10.1016/j.prp.2023.154972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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