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Article

Mutational burden and chromosomal aneuploidy synergistically predict survival from radiotherapy in non-small cell lung cancer.

Communications biology - 29 Jan 2021

Jia Qingzhu, Chu Qian, Zhang Anmei, Yu Jing, Liu Fangfang, Qian Kaiyu, Xiao Yu, Wang Xue, Yang Ying, Zhao Yi, He Ji, Li Guanghui, Wan Yisong Y, Xie Conghua, Zhu Bo

Abstract excerpt

Therapeutic radiation can result in substantially different survival outcomes for patients with non-small cell lung cancer (NSCLC). Measures for identification of patients who can benefit most throughout radiotherapy remain limited. In this retrospective study, survival analysis was performed based on a discovery cohort from TCGA and a validation cohort from three independent hospitals. Tumor mutational burden...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33514859
DOI: 10.1038/s42003-021-01657-6
PMCID: PMC7846582

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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