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Article

Molecular mechanism of radiation tolerance in lung adenocarcinoma cells using single-cell RNA sequencing.

Journal of cellular and molecular medicine - 1 May 2024

Chang Feiyun, Xi Bozhou, Chai Xinchun, Wang Xiuyan, Ma Manyuan, Fan Yafeng

Abstract excerpt

The efficacy of radiotherapy, a cornerstone in the treatment of lung adenocarcinoma (LUAD), is profoundly undermined by radiotolerance. This resistance not only poses a significant clinical challenge but also compromises patient survival rates. Therefore, it is important to explore this mechanism for the treatment of LUAD. Multiple public databases were used for single-cell RNA sequencing (scRNA-seq) data. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38760895
DOI: 10.1111/jcmm.18378
PMCID: PMC11101670

Genes

PIF1
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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