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Production of light-coloured, low heat-absorbing Holstein Friesian cattle by precise embryo-mediated genome editing.

Reproduction, fertility, and development - 1 Dec 2023

Wei Jingwei, Brophy Brigid, Cole Sally-Ann, Leath Shane, Oback Björn, Boch Jens, Wells David N, Laible Götz

Abstract excerpt

CONTEXT: Genome editing enables the introduction of beneficial sequence variants into the genomes of animals with high genetic merit in a single generation. This can be achieved by introducing variants into primary cells followed by producing a live animal from these cells by somatic cell nuclear transfer cloning. The latter step is associated with low efficiencies and developmental problems due to incorrect...

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PMID: 38064192
DOI: 10.1071/RD23163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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