Article
Toward Practical Embryo Genomic Selection in Cattle: An Optimized Workflow Enabling High-Accuracy Breeding Value Prediction Without Compromising Embryo Survival.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 15 Apr 2026
Zhang Jingyu, Liu Zhize, Shen Hang, Zhao Mengmeng, Teng Jun, Wang Yubing, Liu Guangyao, Ye Boxuan, Zhang Zhenni, Zhang Qin, Tian Jianhui, An Lei, Wang Yinjuan
Abstract excerpt
The implementation of embryo genomic selection (EGS) is constrained by the lack of a standardized workflow that balances high genotyping accuracy with the preservation of embryo viability, particularly given embryonic heterogeneity. To address this, we systematically optimized the critical steps of trophectoderm biopsy and whole-genome amplification, establishing a diameter-stratified strategy that links embryo...
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