Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Holstein Friesian dairy cattle edited for diluted coat color as a potential adaptation to climate change.

BMC genomics - 26 Nov 2021

Laible G, Cole S-A, Brophy B, Wei J, Leath S, Jivanji S, Littlejohn M D, Wells D N

Abstract excerpt

BACKGROUND: High-producing Holstein Friesian dairy cattle have a characteristic black and white coat, often with large proportions of black. Compared to a light coat color, black absorbs more solar radiation which is a contributing factor to heat stress in cattle. To better adapt dairy cattle to rapidly warming climates, we aimed to lighten their coat color by genome editing. RESULTS: Using gRNA/Cas9-mediated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Climate Change
Share to Gene Editing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heat-Shock Response

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 34836496
DOI: 10.1186/s12864-021-08175-z
PMCID: PMC8626976

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Holstein Friesian dairy cattle edited for diluted coat color as a potential adaptation to climate change.PMID 34836496Read ↗

Production of light-coloured, low heat-absorbing Holstein Friesian cattle by precise embryo-mediated genome editing.Semantic proximity Read ↗

Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene.Semantic proximity Read ↗

Reverse genetic screen for loss-of-function mutations uncovers a frameshifting deletion in the melanophilin gene accountable for a distinctive coat color in Belgian Blue cattle.Semantic proximity Read ↗

PMEL p.Leu18del dilutes coat color of Kumamoto sub-breed of Japanese Brown cattle.Semantic proximity Read ↗

Uncovering genes underlying coat color variation in indigenous cattle breeds through genome-wide positive selection.Semantic proximity Read ↗

The genomes of precision edited cloned calves show no evidence for off-target events or increased <i>de novo</i> mutagenesisSemantic proximity Read ↗

Genetic effects on coat colour in cattle: dilution of eumelanin and phaeomelanin pigments in an F2-Backcross Charolais x Holstein population.Semantic proximity Read ↗

The genomes of precision edited cloned calves show no evidence for off-target events or increased de novo mutagenesis.Semantic proximity Read ↗

Red coat color in Holstein cattle is associated with a deletion in the MSHR gene.Semantic proximity Read ↗

Convergent changes in melanocortin receptor 1 gene are associated with black-headed coat color in sheep.Semantic proximity Read ↗

Fifteen Shades of Grey: Combined Analysis of Genome-Wide SNP Data in Steppe and Mediterranean Grey Cattle Sheds New Light on the Molecular Basis of Coat Color.Semantic proximity Read ↗

Biology of epidermal and hair pigmentation in cattle: a mini-review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.