Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell histone chaperones patterns guide intercellular communication of tumor microenvironment that contribute to breast cancer metastases

6 Dec 2023

Abstract excerpt

BACKGROUND: Histone chaperones (HCs) are crucial for governing genome stability and gene expression in multiple cancers. However, the functioning of HCs in the tumor microenvironment (TME) is still not clearly understood. METHODS: Self-tested single-cell RNA-seq data derived from 6 breast cancer (BC) patients with brain and liver metastases were reanalyzed by nonnegative matrix factorization (NMF) algorithm for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Genomics and Chromatin Dynamics
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38057779
DOI: 10.1186/s12935-023-03166-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell histone chaperones patterns guide intercellular communication of tumor microenvironment that contribute to breast cancer metastasesPMID 38057779Read ↗

Multi-omics analyses of the heterogenous immune microenvironment in triple-negative breast cancer implicate UQCRFS1 potentiates tumor progressionSemantic proximity Read ↗

Single-cell and spatial transcriptomic analysis reveals tumor cell heterogeneity and underlying molecular program in colorectal cancerSemantic proximity Read ↗

Dissection of triple-negative breast cancer microenvironment and identification of potential therapeutic drugs using single-cell RNA sequencing analysisSemantic proximity Read ↗

Single-cell RNA sequencing reveals route-specific remodeling of the tumor microenvironment and identifies predictive factors of breast cancer metastasisSemantic proximity Read ↗

Single-cell transcriptome analysis reveals evolutionarily conserved features during the transition from normal breast stromal cells to cancer-associated fibroblastsSemantic proximity Read ↗

Single-cell Histone deacetylation factor regulator patterns guide intercellular communication of tumor microenvironment that contribute to colorectal cancer progression and immunotherapySemantic proximity Read ↗

Single‐cell RNA sequencing elucidated the landscape of breast cancer brain metastases and identified ILF2 as a potential therapeutic targetSemantic proximity Read ↗

Elucidating immune-related gene transcriptional programs via factorization of large-scale RNA-profilesSemantic proximity Read ↗

Unveiling functional heterogeneity in breast cancer multicellular tumor spheroids through single-cell RNA-seqSemantic proximity Read ↗

Deciphering Cellular Ecosystems Driving Tumor Progression and Immune Escape from Spatial Transcriptomics and Single-Cell with COMPOTESSemantic proximity Read ↗

Multi-cellular phenotypic dynamics during the progression of breast tumorsSemantic proximity Read ↗

Pan-cancer single cell and spatial transcriptomics analysis deciphers the molecular landscapes of senescence related cancer-associated fibroblasts and reveals its predictive value in neuroblastoma via integrated multi-omics analysis and machine learningSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.