Article

Elucidating immune-related gene transcriptional programs via factorization of large-scale RNA-profiles

2024-05-14

Abstract excerpt

<h4>Summary</h4> Recent developments in immunotherapy, including immune checkpoint blockade (ICB) and adoptive cell therapy, have encountered challenges such as immune-related adverse events and resistance, especially in solid tumors. To advance the field, a deeper understanding of the molecular mechanisms behind treatment responses and resistance is essential. However, the lack of functionally characterized immu...

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Identifiers and source

Literature Corpus work: 183e61dc-37f9-56ac-bb32-b42d669e176d
DOI: 10.1101/2024.05.10.593433

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