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Article

A novel invasive Streptococcus pyogenes variant sublineage derived through recombinational replacement of the emm12 genomic region.

Scientific reports - 6 Dec 2023

Unoarumhi Yvette, Davis Morgan L, Rowe Lori A, Mathis Saundra, Li Zhongya, Chochua Sopio, Li Yuan, McGee Lesley, Metcalf Benjamin J, Lee Justin S, Beall Bernard

Abstract excerpt

Group A streptococcal strains potentially acquire new M protein gene types through genetic recombination (emm switching). To detect such variants, we screened 12,596 invasive GAS genomes for strains of differing emm types that shared the same multilocus sequence type (ST). Through this screening we detected a variant consisting of 16 serum opacity factor (SOF)-positive, emm pattern E, emm82 isolates that were...

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Identifiers

PMID: 38057343
DOI: 10.1038/s41598-023-48035-2
PMCID: PMC10700362

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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