Article
Array of M protein gene subtypes in 1064 recent invasive group A streptococcus isolates recovered from the active bacterial core surveillance.
The Journal of infectious diseases - 15 Nov 2003
Li Zhongya, Sakota Varja, Jackson Delois, Franklin Alma Ruth, Beall Bernard
Abstract excerpt
Using sequence analysis to detect variation within the hypervariable M protein N terminus, we found 41 emm types encompassing 81 subtypes, among 1064 consecutive invasive group A streptococcus isolates from a recent multistate, population-based surveillance. Seventeen of the 30 emm types represented by multiple isolates displayed multiple subtypes. Most subtypes differed from reference strain emm sequences as a...
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