Article
Emergence of a New Highly Successful Acapsular Group A Streptococcus Clade of Genotype emm89 in the United Kingdom.
mBio - 14 Jul 2015
Turner Claire E, Abbott James, Lamagni Theresa, Holden Matthew T G, David Sophia, Jones Michael D, Game Laurence, Efstratiou Androulla, Sriskandan Shiranee
Abstract excerpt
UNLABELLED: Group A Streptococcus (GAS) genotype emm89 is increasingly recognized as a leading cause of disease worldwide, yet factors that underlie the success of this emm type are unknown. Surveillance identified a sustained nationwide increase in emm89 invasive GAS disease in the United Kingdom, prompting longitudinal investigation of this genotype. Whole-genome sequencing revealed a recent dramatic shift in...
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