Article
An excitatory projection from the basal forebrain to the ventral tegmental area that underlies anorexia-like phenotypes.
Neuron - 7 Feb 2024
Cai Jing, Jiang Yanyan, Xu Yuanzhong, Jiang Zhiying, Young Claire, Li Hongli, Ortiz-Guzman Joshua, Zhuo Yizhou, Li Yulong, Xu Yong, Arenkiel Benjamin R, Tong Qingchun
Abstract excerpt
Maladaptation in balancing internal energy needs and external threat cues may result in eating disorders. However, brain mechanisms underlying such maladaptations remain elusive. Here, we identified that the basal forebrain (BF) sends glutamatergic projections to glutamatergic neurons in the ventral tegmental area (VTA) in mice. Glutamatergic neurons in both regions displayed correlated responses to various...
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