Article
Circulating Biomarkers and Risk of Hypertension: A Two-Sample Mendelian Randomisation Study.
Heart, lung & circulation - 1 Dec 2023
Li Jin, Yao Yue-Xian, Yao Pei-Sen
Abstract excerpt
OBJECTIVE: This study systematically assessed circulating proteins to identify new serum biomarkers and risk of hypertension using Mendelian randomisation. METHODS: The associations between 4,782 human circulating proteins and the risk of hypertension were evaluated using two-sample Mendelian randomisation. The FinnGen study demonstrated a link between genetic predisposition and hypertension in 85,438 cases and...
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