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Article

The causal association between 91 inflammatory Circulating proteins and intracerebral hemorrhage: A bidirectional two-sample Mendelian randomization study.

Neurosurgical review - 26 Aug 2025

Liu Chaoyi, Lei Dan, Min Qiang

Abstract excerpt

BACKGROUND: Intracerebral hemorrhage (ICH), a subtype of stroke, is associated with high incidence and disability rates. The link between inflammatory circulating proteins and ICH is still not definitively established. Our research sets out to delve into this mystery by examining the potential causal connection between 91 such proteins and ICH, employing a sophisticated two-sample Mendelian randomization approach...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 40855041
DOI: 10.1007/s10143-025-03764-y

Genes

CXCL9
CXCL1

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