The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.

doi:10.1038/sdata.2018.185

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The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.

Scientific data - 11 Sept 2018

Wang Minghui, Beckmann Noam D, Roussos Panos, Wang Erming, Zhou Xianxiao, Wang Qian, Ming Chen, Neff Ryan, Ma Weiping, Fullard John F, Hauberg Mads E, Bendl Jaroslav, Peters Mette A, Logsdon Ben, Wang Pei, Mahajan Milind, Mangravite Lara M, Dammer Eric B, Duong Duc M, Lah James J, Seyfried Nicholas T, Levey Allan I, Buxbaum Joseph D, Ehrlich Michelle, Gandy Sam, Katsel Pavel, Haroutunian Vahram, Schadt Eric, Zhang Bin

Abstract excerpt

Alzheimer's disease (AD) affects half the US population over the age of 85 and is universally fatal following an average course of 10 years of progressive cognitive disability. Genetic and genome-wide association studies (GWAS) have identified about 33 risk factor genes for common, late-onset AD (LOAD), but these risk loci fail to account for the majority of affected cases and can neither provide clinically...

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PMID: 30204156
DOI: 10.1038/sdata.2018.185
PMCID: PMC6132187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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