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Article

ABC transporters are predictors of treatment failure in acute myeloid leukaemia

30 Nov 2023

Abstract excerpt

INTRODUCTION: To date, no chemoresistance predictors are included in acute myeloid leukaemia (AML) prognostic scoring systems to distinguish responding and refractory AML patients prior to chemotherapy. ABC transporters have been described as altering AML chemosensitivity; however, a relevant study investigating their role at various molecular levels was lacking. METHODS: Gene expression, genetic variants,...

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PMID: 38039756
DOI: 10.1016/j.biopha.2023.115930

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