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Revisiting ABC Transporters and Their Clinical Significance in Glioblastoma

15 Jan 2025

Abstract excerpt

Background: The multiple drug-resistant phenomenon has long since plagued the effectiveness of various chemotherapies used in the treatment of patients with glioblastoma (GBM), which is still incurable to this day. ATP-binding cassette (ABC) transporters function as drug transporters and have been touted to be the main culprits in developing resistance to xenobiotic drugs in GBM. Methods: This review...

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PMID: 39861164
DOI: 10.3390/ph18010102

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