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CLK3 promotes tumor proliferation by activating MYC signaling

17 Sept 2024

Abstract excerpt

Colorectal cancer (CRC) ranks among the leading causes of cancer-related mortality worldwide, posing a significant public health challenge. Despite advancements in treatment strategies, prognosis for advanced CRC remains poor. Here, we investigate the role of CLK3 and its interaction with the c-Myc signaling pathway in CRC progression. Our study reveals significant overexpression of CLK3 in CRC tumor tissues,...

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PMID: 39289754
DOI: 10.1186/s13008-024-00132-y

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