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Article

H3K27-altered diffuse midline gliomas with MAPK pathway alterations: Prognostic and therapeutic implications.

Journal of neuropathology and experimental neurology - 22 Dec 2023

Gestrich Catherine, Grieco Kristina, Lidov Hart G, Baird Lissa C, Fehnel Katie P, Yeo Kee Kiat, Meredith David M, Alexandrescu Sanda

Abstract excerpt

Large-scale sequencing led to the identification of driver molecular alterations such as FGFR1 and BRAF in occasional diffuse midline gliomas (DMGs) H3K27-mutant but their significance has not been completely explored. We evaluated these associations in our institutional cohorts. We searched our archives for H3K2M7-mutant gliomas and analyzed the co-occurring genetic alterations. The demographics, clinical...

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Source

Identifiers

PMID: 38037182
DOI: 10.1093/jnen/nlad103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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