Article
Clinical significance of WT1 in the evaluation of therapeutic effect and prognosis of non-M3 acute myeloid leukemia.
Cancer biology & therapy - 31 Dec 2023
Yu Tingyu, Zhan Qian, Yan Xinyu, Luo Xiaohua, Wang Xin, Tang Xiaoqiong, Zhang Hongbin, Yang Zesong, Chen Jianbin, Liu Lin, Wang Li
Abstract excerpt
To explore the clinical significance and prognosis of acute myeloid leukemia (AML) patients with WT1 mutations.In total, the clinical data of 269 adult patients with non-M3 AML were considered retrospectively. From these patients, 153 carried WT1 mutation whereas 116 were negative. WT1 mutation positive patients were further divided into WT1 low expression and high expression groups base on the expression level...
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