Article
Overexpressed WT1 exhibits a specific immunophenotype in intermediate and poor cytogenetic risk acute myeloid leukemia.
Annals of hematology - 1 Feb 2020
Wang Xiao-Rui, Chang Yan, Yuan Xiao-Ying, Wang Ya-Zhe, Qin Ya-Zhen, Ruan Guo-Rui, Lai Yue-Yun, Liu Yan-Rong
Abstract excerpt
Many studies have confirmed that overexpressed WT1 exists in leukemic cells, especially in AML. However, the immunophenotypic features of this sort of leukemic cells remain to be unclarified. We retrospectively analyzed the immunophenotype of 283 newly diagnosed AML patients with intermediated and poor cytogenetic risk to evaluate the correlation between phenotype and WT1 overexpression. EVI1 transcripts,...
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