Article
High WT1 expression predicted induction chemotherapy failure in acute myeloid leukemia patients with non-favorable cytogenetic risk.
Clinical and experimental medicine - 1 Oct 2023
Xu Nan, Chen Wen-Min, Li Ling-Di, Long Ling-Yu, Wang Xu, Jiang Qian, Jiang Hao, Huang Xiao-Jun, Qin Ya-Zhen
Abstract excerpt
The prognostic significance of WT1 expression at diagnosis in acute myeloid leukemia (AML) remains obscure, and subgroup analysis is the way for clarification. We previously reported the results in t(8;21) AML. In this study, 437 consecutive adult AML patients with non-favorable cytogenetic risk were enrolled. All patients were tested WT1 transcript levels using real-time quantitative PCR at diagnosis;...
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