Article
Cisplatin exposure alters tRNA-derived small RNAs but does not affect epimutations in C. elegans.
BMC biology - 29 Nov 2023
Fallet Manon, Wilson Rachel, Sarkies Peter
Abstract excerpt
BACKGROUND: The individual lifestyle and environment of an organism can influence its phenotype and potentially the phenotype of its offspring. The different genetic and non-genetic components of the inheritance system and their mutual interactions are key mechanisms to generate inherited phenotypic changes. Epigenetic changes can be transmitted between generations independently from changes in DNA sequence. In...
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