Role of pre-existing immunity in driving the dengue virus serotype 2 genotype shift in the Philippines: A retrospective analysis of serological data.

doi:10.1016/j.ijid.2023.11.025

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Article

Role of pre-existing immunity in driving the dengue virus serotype 2 genotype shift in the Philippines: A retrospective analysis of serological data.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Feb 2024

Balingit Jean Claude, Dimamay Mark Pierre S, Suzuki Ryosuke, Matsuda Mami, Xayavong Dalouny, Ngwe Tun Mya Myat, Matias Ronald R, Natividad Filipinas F, Moi Meng Ling, Takamatsu Yuki, Culleton Richard, Buerano Corazon C, Morita Kouichi

Abstract excerpt

OBJECTIVE: The invasion of dengue virus (DENV)-2 Cosmopolitan genotype into the Philippines, where the Asian II genotype previously circulated challenges the principle of dengue serotype-specific immunity. Assessment of antibodies in this population may provide a mechanistic basis for how new genotypes emerge in dengue-endemic areas. METHODS: We evaluated the neutralizing antibody (nAb) and antibody-dependent...

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PMID: 38029834
DOI: 10.1016/j.ijid.2023.11.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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