Article
Molecular epidemiology of dengue 2 viruses in the Philippines: genotype shift and local evolution.
The American journal of tropical medicine and hygiene - 1 Oct 2005
Salda Leonora T D, Parquet Maria D C, Matias Ronald R, Natividad Filipinas F, Kobayashi Noboyuki, Morita Kouichi
Abstract excerpt
The pre-membrane (prM) and envelope (E) genes of 41 viruses isolated from dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS) patients from 1995 to 2002 were sequenced to determine the genetic variability of dengue 2 (DENV 2) viruses in the Philippines. The envelope sequence data were compared with a global sample of DENV 2 obtained from GenBank. Phylogenetic analysis revealed that...
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