Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and human

23 Mar 2023

Abstract excerpt

Cylicins are testis-specific proteins, which are exclusively expressed during spermiogenesis. In mice and humans, two Cylicins, the gonosomal X-linked Cylicin 1 ( Cylc1/CYLC1 ) and the autosomal Cylicin 2 ( Cylc2/CYLC2 ) genes, have been identified. Cylicins are cytoskeletal proteins with an overall positive charge due to lysine-rich repeats. While Cylicins have been localized in the acrosomal region of round...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microtubule and mitosis dynamics
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38013430
DOI: 10.7554/elife.86100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and humanPMID 38013430Read ↗

Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and humanSemantic proximity Read ↗

Disruption in <i>CYLC1</i> leads to acrosome detachment, sperm head deformity, and male in/subfertility in humans and miceSemantic proximity Read ↗

Mutations in CCIN cause teratozoospermia and male infertility.Semantic proximity Read ↗

Leucine-rich Repeat Protein LRRC37A Acts as a Molecular Scaffold Coordinating IAM-PT-NE Complex Assembly and Sperm Head MorphogenesisSemantic proximity Read ↗

A novel atypical sperm centriole is functional during human fertilizationSemantic proximity Read ↗

PCM1 orchestrates centrosomal and flagellar protein transport to promote sperm maturationSemantic proximity Read ↗

Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in miceSemantic proximity Read ↗

CCDC28A deficiency causes head-tail coupling defects and immotility in murine spermatozoaSemantic proximity Read ↗

Molecular characterization of mammalian cylicin, a basic protein of the sperm head cytoskeletonSemantic proximity Read ↗

The Genetic Defects of N-DRC in Male Infertility.Semantic proximity Read ↗

Testis-specific actin-like 7A (ACTL7A) is an indispensable protein for subacrosomal-associated F-actin formation, acrosomal anchoring, and male fertilitySemantic proximity Read ↗

<i>Spata6</i> is required for normal assembly of the sperm connecting piece and tight head–tail conjunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.