Article
Mutations in CCIN cause teratozoospermia and male infertility.
Science bulletin - 31 Oct 2022
Fan Yong, Huang Chenhui, Chen Juan, Chen Yanyan, Wang Yan, Yan Zhiguang, Yu Weina, Wu Haibo, Yang Ying, Nie Leitong, Huang Sijia, Wang Fangfang, Wang Haoyu, Hua Yunfeng, Lyu Qifeng, Kuang Yanping, Lei Ming
Abstract excerpt
Teratozoospermia is usually associated with defective spermiogenesis and is a disorder with considerable genetic heterogeneity. Although previous studies have identified several teratozoospermia-associated genes, the etiology remains unknown for a majority of affected men. Here, we identified a homozygous missense mutation and a compound heterozygous mutation of CCIN in patients suffering from teratozoospermia....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.