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Endothelial cells adopt a pro-reparative immune responsive signature during cardiac injury

27 Nov 2023

Abstract excerpt

Modulation of the heart’s immune microenvironment is crucial for recovery after ischemic events such as myocardial infarction (MI). Endothelial cells (ECs) can have immune regulatory functions; however, interactions between ECs and the immune environment in the heart after MI remain poorly understood. We identified an EC-specific IFN responsive and immune regulatory gene signature in adult and pediatric heart...

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PMID: 38012001
DOI: 10.26508/lsa.202201870

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