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Article

Genetic evidence for causal effects of leukocyte counts on risk for rheumatoid arthritis.

Scientific reports - 26 Nov 2023

You Jin-Mei, Zhang Yao-Chen, Fan Ke-Yi, Bai Shang-Kai, Zhang Zi-Yu, Zhang He-Yi, Cheng Ting, Huo Yue-Hong, Wang Cai-Hong, Li Xiao-Feng, Zhang Sheng-Xiao

Abstract excerpt

Rheumatoid arthritis (RA) is an autoimmune disease characterized by the accumulation of leukocytes and inflammatory mediators within the synovial tissue. Leukocyte counts are proposed to play a role in the pathogenesis of RA. However, the causality remains unclear. To investigate the causal relationship between various leukocytes and RA by implementing two-sample univariable Mendelian Randomization (MR) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38008752
DOI: 10.1038/s41598-023-46888-1
PMCID: PMC10679084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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