Analysis of the causal relationship between immune cells and rheumatoid arthritis from the perspective of genetic variation: a bidirectional two-sample Mendelian randomization study.

Abstract excerpt

BACKGROUND: Immune factors are crucial in the pathogenesis of rheumatoid arthritis (RA), and immune cells play a key role in the development of RA. However, there is still disagreement regarding the specific roles of each type of immune cell in the pathological process of RA. METHODS: This study used bidirectional two-sample Mendelian randomization (MR) analysis to determine the causal relationship between immune...

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• Arthritis, Rheumatoid
• Genetic Predisposition to Disease
• Genetic Variation
• Mendelian Randomization Analysis
• Phenotype