Back to search

Article

scRNA-Seq Combined with scPagwas Analysis Identifies GNG7 as a Core Gene in Lung Adenocarcinoma

2025-09-23

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective:</bold> Lung cancer is a leading cause of cancer-related deaths globally, with lung adenocarcinoma (LUAD) showing high incidence in non-smoking cases. Over one million die annually from lung cancer, and LUAD presents treatment challenges due to complex biological behavior, variability in therapeutic responses, and pronounced heterogeneity (within tumor cells and the m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ea517048-319e-5fe1-a73e-b13d6ade136a
DOI
10.21203/rs.3.rs-7388573/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
scRNA-Seq Combined with scPagwas Analysis Identifies GNG7 as a Core Gene in Lung AdenocarcinomaDOI 10.21203/rs.3.rs-7388573/v1
Integration of Single-Cell RNA Sequencing and Bulk RNA Sequencing Data to Establish and Validate a Prognostic Model for Patients With Lung AdenocarcinomaSemantic proximity
Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancerSemantic proximity
Integrated analysis of single-cell RNA-seq and bulk RNA-seq reveals immune suppression subtypes and establishes a novel signature for determining the prognosis in lung adenocarcinomaSemantic proximity
Dissecting heterogeneity and immune cell populations in non-small cell lung cancer by single cell RNA sequencingSemantic proximity
A single-cell characterised signature integrating heterogeneity and microenvironment of lung adenocarcinoma for prognostic stratificationSemantic proximity
Identification of N7-methylguanosine related signature for prognosis and immunotherapy efficacy prediction in lung adenocarcinomaSemantic proximity
Integrated whole-exome and bulk transcriptome sequencing delineates the dynamic evolution from preneoplasia to invasive lung adenocarcinoma featured with ground-glass nodules.Semantic proximity
Genome-wide association, single-cell, and spatial transcriptomics analyses reveal the role of the STK24-expressing positive cells in LUAD progression and the tumor microenvironment, identifying STK24 as a potential therapeutic target.Semantic proximity
Differential prognostic impact and potential molecular mechanisms of PCDHGA12 expression in lung adenocarcinoma and squamous cell carcinoma.Semantic proximity
Prognostic and immunological potential of AC012236.1/hsa-miR-30d-5p ceRNA AVEN by integrated analysis of single-cell and bulk RNA-seq in lung adenocarcinomaSemantic proximity
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancerSemantic proximity
Purine metabolism in lung adenocarcinoma: A single‐cell analysis revealing prognostic and immunotherapeutic insightsSemantic proximity
Select a neighboring publication to make it the new centre.