Article
Shared Genetic Architecture between Parkinson's Disease and Brain Structural Phenotypes.
Movement disorders : official journal of the Movement Disorder Society - 1 Dec 2023
Ma Dong-Rui, Li Shuang-Jie, Shi Jing-Jing, Liang Yuan-Yuan, Hu Zheng-Wei, Hao Xiao-Yan, Li Meng-Jie, Guo Meng-Nan, Zuo Chun-Yan, Yu Wen-Kai, Mao Cheng-Yuan, Tang Mi-Bo, Zhang Chan, Xu Yu-Ming, Wu Jun, Sun Shi-Lei, Shi Chang-He
Abstract excerpt
BACKGROUND: Patients with Parkinson's disease (PD) have consistently demonstrated brain structure abnormalities, indicating the presence of shared etiological and pathological processes between PD and brain structures; however, the genetic relationship remains poorly understood. OBJECTIVE: The aim of this study was to investigate the extent of shared genetic architecture between PD and brain structural phenotypes...
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