Article
Mutational Landscape of Cholangiocarcinoma According to Different Etiologies: A Review.
Cells - 22 Apr 2023
Tavolari Simona, Brandi Giovanni
Abstract excerpt
Recent next-generation sequencing (NGS) studies on large cohorts of cholangiocarcinoma (CCA) patients have clearly revealed the extreme intra- and inter-tumoral molecular heterogeneity that characterizes this malignancy. The lack of a stereotyped molecular signature in CCA makes the identification of actionable therapeutic targets challenging, making it mandatory to have a better understanding of the origin of...
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