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USP18 enhances dengue virus replication by regulating mitochondrial DNA release

17 Nov 2023

Abstract excerpt

Dengue virus (DENV) infection remains a challenging health threat worldwide. Ubiquitin-specific protease 18 (USP18), which preserves the anti-interferon (IFN) effect, is an ideal target through which DENV mediates its own immune evasion. However, much of the function and mechanism of USP18 in regulating DENV replication remains incompletely understood. In addition, whether USP18 regulates DENV replication merely...

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PMID: 37978268
DOI: 10.1038/s41598-023-47584-w

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