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Intracellular energy controls dynamics of stress-induced ribonucleoprotein granules

23 Sept 2022

Abstract excerpt

Energy metabolism and membraneless organelles have been implicated in human diseases including neurodegeneration. How energy deficiency regulates ribonucleoprotein particles such as stress granules (SGs) is still unclear. Here we identified a unique type of granules induced by energy deficiency under physiological conditions and uncovered the mechanisms by which the dynamics of diverse stress-induced granules are...

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PMID: 36151083
DOI: 10.1038/s41467-022-33079-1

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