Article
The HLA-C*04: 01/KIR2DS4 gene combination and human leukocyte antigen alleles with high population frequency drive rate of HIV disease progression.
AIDS (London, England) - 13 Mar 2015
Olvera Alex, Pérez-Álvarez Susana, Ibarrondo Javier, Ganoza Carmela, Lama Javier R, Lucchetti Aldo, Cate Steven, Hildebrand William, Bernard Nicole, Gomez Lupe, Sanchez Jorge, Brander Christian
Abstract excerpt
OBJECTIVE: The objective of this study is to identify human leukocyte antigen (HLA) class I and killer-cell immunoglobulin-like receptor (KIR) genotypes associated with different risks for HIV acquisition and HIV disease progression. DESIGN: A cross-sectional study of a cohort of 468 high-risk individuals (246 HIV-positive and 222 HIV-negative) from outpatient clinics in Lima (Perú). METHODS: The cohort was...
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