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Targeting the DNA repair pathway for breast cancer therapy: Beyond the molecular subtypes

9 Nov 2023

Abstract excerpt

DNA repair is a vital mechanism in cells that protects against DNA damage caused by internal and external factors. It involves a network of signaling pathways that monitor and transmit damage signals, activating various cellular activities to repair DNA damage and maintain genomic integrity. Dysfunctions in this repair pathway are strongly associated with the development and progression of cancer. However, they...

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PMID: 37951025
DOI: 10.1016/j.biopha.2023.115877

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