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Article

Role of PARP Inhibitors: A New Hope for Breast Cancer Therapy.

International journal of molecular sciences - 19 Mar 2025

De Kamalendu, Jana Malabendu, Chowdhury Bhabadeb, Calaf Gloria M, Roy Debasish

Abstract excerpt

Tumors formed by the unchecked growth of breast cells are known as breast cancer. The second most frequent cancer in the world is breast cancer. It is the most common cancer among females. In 2022, 2,296,840 women were diagnosed with breast cancer. The therapy of breast cancer is evolving through the development of Poly (ADP-ribose) polymerase (PARP) inhibitors, which are offering people with specific genetic...

Read the complete abstract on PubMed

Topics

Humans
Poly(ADP-ribose) Polymerase Inhibitors
Breast Neoplasms
Female
BRCA1 Protein
BRCA2 Protein
Antineoplastic Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 40141415
DOI: 10.3390/ijms26062773
PMCID: PMC11942994

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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