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Article

d-Galactose induces the senescence and phenotype switch of corpus cavernosum smooth muscle cells.

Journal of cellular physiology - 1 Jan 2024

Hu Daoyuan, Ge Yunlong, Ye Lei, Xi Yuhang, Chen Jialiang, Zhu Wenliang, Wang Zhenqing, Sun Zhuolun, Su Ying, Wang Dejuan, Xiao Shiwei, Qiu Jianguang

Abstract excerpt

Studies regarding age-related erectile dysfunction (ED) based on naturally aging models are limited by their high costs, especially for the acquisition of primary cells from the corpus cavernosum. Herein, d-galactose ( d-gal) was employed to accelerate cell senescence, and the underlying mechanism was explored. As predominant functional cells involved in the erectile response, corpus cavernosum smooth muscle...

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Identifiers

PMID: 37942832
DOI: 10.1002/jcp.31150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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