Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic transition of corpus cavernosum smooth muscle cells subjected to hypoxia.

Cell and tissue research - 1 Sept 2014

Lv Bodong, Zhao Jianfeng, Yang Fan, Huang Xiaojun, Chen Gang, Yang Kebing, Liu Shanshan, Fan Chunlei, Fu Huiying, Chen Zhaodian

Abstract excerpt

Corpora cavernosum smooth muscle cells (CCSMCs) have been shown to play a critical role in the male erectile response and are involved in the pathogenesis of multiple causes of erectile dysfunction (ED). To investigate the underlying mechanisms, we studied the changes that CCSMCs undergo under hypoxic conditions in vitro. The identified and characterized CCSMCs were exposed to hypoxia for 48 h and its phenotypic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Hypoxia
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Separation

Share to Extracellular Matrix Proteins

Share to Hypoxia-Inducible Factor 1, alpha Subunit

Share to Myocytes, Smooth Muscle

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 24913687
DOI: 10.1007/s00441-014-1902-0

Genes

CNN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic transition of corpus cavernosum smooth muscle cells subjected to hypoxia.PMID 24913687Read ↗

[henotypic modulation of corporal cavernosum smooth muscle cells and erectile dysfunction: Advances in studies].Semantic proximity Read ↗

The platelet-derived growth factor receptor/STAT3 signaling pathway regulates the phenotypic transition of corpus cavernosum smooth muscle in rats.Semantic proximity Read ↗

Krüppel-Like Factor 5 Inhibition Rescues Cavernous Nerve-Injured Erectile Dysfunction by Preventing Phenotypic Switch and Mitochondrial Dysfunction-Dependent Apoptosis in Corpus Cavernosum Smooth Muscle Cells.Semantic proximity Read ↗

Maintenance of the contractile phenotype in corpus cavernosum smooth muscle cells by Myocardin gene therapy ameliorates erectile dysfunction in bilateral cavernous nerve injury rats.Semantic proximity Read ↗

Bilirubin preserves corpus cavernosum smooth muscle phenotype via inhibition of ferroptosis: Implications for oxidative stress-related erectile dysfunctionSemantic proximity Read ↗

Phenotypic modulation of vascular smooth muscle cells in the corpus spongiosum surrounding the urethral plate in hypospadias.Semantic proximity Read ↗

Characterization of corpus cavernosum smooth muscle cell phenotype in diabetic rats with erectile dysfunction.Semantic proximity Read ↗

Phenotype and function of smooth muscle cells derived from the human normal great saphenous vein in response to hypoxia.Semantic proximity Read ↗

[Phenotypic modulation of corpus cavernous smooth musle cells and its influencing factors].Semantic proximity Read ↗

Single-cell transcriptome atlas of the human corpus cavernosumSemantic proximity Read ↗

d-Galactose induces the senescence and phenotype switch of corpus cavernosum smooth muscle cells.Semantic proximity Read ↗

[Phenotypic transformation of corpus cavernosum smooth muscle cells in hypertensive rats].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.