Article
Biological agents involved in malignant mesothelioma: relevance as biomarkers or therapeutic targets.
Current cancer drug targets - 1 Feb 2010
Crispi Stefania, Cardillo Irene, Spugnini Enrico P, Citro Gennaro, Menegozzo Simona, Baldi Alfonso
Abstract excerpt
Malignant mesothelioma (MM) is a rare, highly aggressive tumor that arises from the surface serosal cells (pleural, peritoneal and pericardial cavities). Epidemiological and clinical data show that there is an association between asbestos exposure and MM development, even if the exact mechanism whereby asbestos induces MM is unknown. The continuing identification and elucidation of the molecular defects involved...
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