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Article

Clinical relevance of somatic mutations in Chinese lung adenocarcinoma and their prognostic implications for survival.

Cancer medicine - 1 May 2024

Li Tongxin, Liu Jie, Zhou Yu, Huang Shengyuan, Wang Dong, Chen Jianrong, Fu Yong, He Ping

Abstract excerpt

BACKGROUND: To comprehensively elucidate the genomic and mutational features of lung cancer cases, and lung adenocarcinoma (LUAD), it is imperative to conduct ongoing investigations into the genomic landscape. In this study, we aim to analyze the somatic mutation profile and assessed the significance of these informative genes utilizing a retrospective LUAD cohort. METHODS: A total of 247 Chinese samples were...

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Identifiers

PMID: 38770632
DOI: 10.1002/cam4.7227
PMCID: PMC11106684

Genes

EGFR
KRAS
LRP1B
RBM10
TP53
ALK
BRAF
BRCA2
PDGFRA

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