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Article

Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: distinct responses to stimuli.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2006

Deng David Xing-Fei, Spin Joshua M, Tsalenko Anya, Vailaya Aditya, Ben-Dor Amir, Yakhini Zohar, Tsao Phil, Bruhn Laurakay, Quertermous Thomas

Abstract excerpt

OBJECTIVE: Phenotypic differences between vascular smooth muscle cell (VSMC) subtypes lead to diverse pathological processes including atherosclerosis, postangioplasty restenosis and vein graft disease. To better understand the molecular mechanisms underlying functional differences among distinct SMC subtypes, we compared gene expression profiles and functional responses to oxidized low-density lipoprotein...

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Share to Coronary Vessels
Share to Guanine Nucleotide Exchange Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor Binding Proteins

Share to Insulin-Like Growth Factor I

Share to Lipoproteins, LDL

Share to Myocytes, Smooth Muscle

Share to Platelet-Derived Growth Factor

Share to Saphenous Vein

Source

Identifiers

PMID: 16456091
DOI: 10.1161/01.ATV.0000208185.16371.97

Genes

CXCL10
CXCL11
CXCL12
IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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