Article
Desmuslin gene knockdown causes altered expression of phenotype markers and differentiation of saphenous vein smooth muscle cells.
Journal of vascular surgery - 1 Sept 2010
Xiao Ying, Huang Zhibin, Yin Henghui, Zhang Hui, Wang Shenming
Abstract excerpt
OBJECTIVE: Phenotypic alterations of vascular smooth muscle cells (VSMCs) appear critical to the development of primary varicose veins. Previous study indicated desmuslin, an intermediate filament protein, was differentially expressed in smooth muscle cells (SMCs) isolated from varicose veins; thus, it was naturally hypothesized that altered desmuslin expression might in turn affect the functioning of VSMCs,...
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