The 1.7 Å crystal structure of the C5a peptidase from Streptococcus agalactiae ( ScpB ) reveals an active site competent for catalysis

Abstract excerpt

Abstract A 1.7 Å structure is presented for an active form of the virulence factor ScpB, the C5a peptidase from Streptococcus agalactiae. The previously reported structure of the ScpB active site mutant exhibited a large separation (~20 Å) between the catalytic His and Ser residues. Significant differences are observed in the catalytic domain between the current and mutant ScpB structures resulting with a high...

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