Article
Complete nucleotide sequence of the streptococcal C5a peptidase gene of Streptococcus pyogenes.
1 Feb 1990
Abstract excerpt
Streptococcal C5a peptidase (SCP), a recently discovered virulence factor of Streptococcus pyogenes, specifically cleaves the human serum chemotaxin C5a near its carboxyl terminus, destroying its ability to serve as a chemoattractant. We previously localized the SCP gene, scpA, to the 5.8-kb insert of the recombinant plasmid pTT1. Here we present the complete nucleotide sequence of scpA and its flanking regions....
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