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Structural and functional characterization of SplA, an exclusively specific protease of <i>Staphylococcus aureus</i>

31 Jan 2009

Abstract excerpt

Staphylococcus aureus is a dangerous human pathogen whose antibiotic resistance is steadily increasing and no efficient vaccine is as yet available. This serious threat drives extensive studies on staphylococcal physiology and pathogenicity pathways, especially virulence factors. Spl (serine protease-like) proteins encoded by an operon containing up to six genes are a good example of poorly characterized secreted...

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PMID: 19175361
DOI: 10.1042/bj20081351

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