Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenome-wide association study of peripheral immune cell populations in Parkinson’s disease

31 Oct 2023

Abstract excerpt

Abstract Understanding the contribution of immune mechanisms to Parkinson’s disease pathogenesis is an important challenge, potentially of major therapeutic implications. To further elucidate the involvement of peripheral immune cells, we studied epigenome-wide DNA methylation in isolated populations of CD14+ monocytes, CD19+ B cells, CD4+ T cells, and CD8+ T cells from Parkinson’s disease patients and healthy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37903812
DOI: 10.1038/s41531-023-00594-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenome-wide association study of peripheral immune cell populations in Parkinson’s diseasePMID 37903812Read ↗

Mapping the peripheral immune landscape of Parkinson’s disease patients with single-cell sequencingSemantic proximity Read ↗

Immunological shifts during early-stage Parkinson’s disease identified with DNA methylation data on longitudinally collected blood samplesSemantic proximity Read ↗

Single-cell RNA sequencing of peripheral blood cells identifies transcriptomic signatures in Parkinson’s diseaseSemantic proximity Read ↗

Immune cell distributions in the blood of healthy individuals at high genetic risk of Parkinson’s diseaseSemantic proximity Read ↗

<i>Trans</i> -pQTL study identifies immune crosstalk between Parkinson and Alzheimer lociSemantic proximity Read ↗

A monocyte gene expression signature in the early clinical course of Parkinson’s diseaseSemantic proximity Read ↗

Immune Cell Distributions in the Blood of Healthy Individuals at High Genetic Risk of Parkinson's Disease.Semantic proximity Read ↗

Heritability enrichment implicates microglia in Parkinson’s disease pathogenesisSemantic proximity Read ↗

Immune Profiling of Parkinson’s Disease Revealed Its Association With a Subset of Infiltrating Cells and Signature GenesSemantic proximity Read ↗

Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in femalesSemantic proximity Read ↗

Regional genetic correlations highlight relationships between neurodegenerative disease loci and the immune system.Semantic proximity Read ↗

Leveraging blood RNA expression to understand Parkinson’s disease heterogeneity and progressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.