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BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1

30 Oct 2023

Abstract excerpt

Macroautophagy/autophagy receptors are essential for the recognition and clearance of specific cargos by selective autophagy, which is essential for maintaining MAPT proteostasis. Previous studies have implicated different autophagy receptors in directing distinct species of MAPT to autophagy, but the underlying mechanisms have not been fully investigated. Here we examine how the autophagy receptors NBR1 and...

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PMID: 37899687
DOI: 10.1080/15548627.2023.2276622

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